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Epigenomics of cellular reaweakening

We are located in the Molecular Genetics Department at the Ohio State University. Our research program is dedicated to investigating chromatin reprogramming and its critical role in quiescence. Quiescence is a fascinating state where cells temporarily cease proliferation, promoting long-term survival. We focus on unraveling the dynamic epigenomic changes underlying this process. We leverage budding yeast and mouse neural stem cells as model systems to dissect the intricate processes that drive cellular reawakening from quiescence. Research in the Cucinotta lab has applications to aging, cancer, and regeneration. The lab will officially open in January 2024, so check back for updates in the new year!

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